Globulins are a group of proteins that includes antibodies. The value is usually calculated as total protein minus albumin.
- Normal range (adults)
- 2–3.5 g/dL (20–35 g/L)
- Sample
- Blood
- Fasting
- Not usually needed
- Also called
- Serum Globulin, GLOB, Total Globulin, Blood Globulin
Globulin normal range
| Group | g/dLConventional units: US, South Asia | g/LSI units: UK, Europe, Australia, international |
|---|---|---|
| Adults | 2–3.5 | 20–35 |
Your report may use either unit system; labs in the Gulf often print both. Ranges also vary slightly between laboratories, so the range printed on your own report is the one to go by.
Why is the Globulin test done?
It gives a rough picture of immune activity and helps interpret liver function.
What does a high Globulin level mean?
A high globulin often means an active immune system or chronic inflammation.
Common causes
- Chronic infections
- Autoimmune disease
- Chronic liver disease
- Rarely, multiple myeloma
Diet and lifestyle tips
- Balanced anti-inflammatory diet
- Stay hydrated
What does a low Globulin level mean?
A low globulin can mean reduced antibody production.
Common causes
- Immune deficiency
- Malnutrition
- Protein loss through gut or kidneys
Diet and lifestyle tips
- Adequate protein and calories
When should you see a doctor?
Your doctor may order protein electrophoresis if globulin is markedly high or low.
Last updated
This page is for general education and is not a diagnosis. Normal ranges differ between laboratories, so always compare your result with the reference range printed on your own report, and discuss abnormal results with your doctor.