Skip to content
MediScanIO
Home Health Info Lab Tests
Hormone Tests

Estradiol (E2)

Estradiol (E2) is the main estrogen in women of reproductive age. Men make small amounts.

Normal range (adults)
Men 10–40 pg/mL (37–147 pmol/L) · Women 12.4–233 pg/mL (46–855 pmol/L)
Sample
Blood
Fasting
Not usually needed
Also called
E2, Oestradiol, 17-Beta Estradiol, Serum Estradiol

Estradiol normal range

Grouppg/mLConventional units: US, South Asiapmol/LSI units: UK, Europe, Australia, international
Men10–4037–147
Women12.4–23346–855

In women, estradiol changes a lot through the menstrual cycle. The female range shown is broad; use your lab's cycle-phase ranges.

Your report may use either unit system; labs in the Gulf often print both. Ranges also vary slightly between laboratories, so the range printed on your own report is the one to go by.

Why is the Estradiol test done?

It is checked for fertility, irregular periods, menopause symptoms and in men with breast enlargement.

What does a high Estradiol level mean?

High estradiol is normal around ovulation and in pregnancy. Persistently high levels can come from hormone treatment, obesity or rare tumours.

Common causes

  • Ovulation or pregnancy
  • Hormone therapy
  • Obesity (fat tissue makes estrogen)
  • Liver disease
  • Rarely, hormone-producing tumours

Diet and lifestyle tips

  • Keep a healthy weight
  • Limit alcohol

What does a low Estradiol level mean?

Low estradiol in women can cause hot flushes, vaginal dryness, missed periods and bone loss.

Common causes

  • Menopause
  • Low body weight or excessive exercise
  • Pituitary problems
  • Premature ovarian insufficiency

Diet and lifestyle tips

  • Eat enough calories
  • Calcium and vitamin D for bone health
  • Weight-bearing exercise such as walking

When should you see a doctor?

Results depend heavily on cycle day; discuss them with your doctor.

Last updated

This page is for general education and is not a diagnosis. Normal ranges differ between laboratories, so always compare your result with the reference range printed on your own report, and discuss abnormal results with your doctor.